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2009年9月例会
一般講演

1. DXA法による実験動物の大腿骨測定

2. ラット胸腺過形成、胸腺腫、腎欠損および腎水腫の診断における画像解析の有用性

3. 動物実験施設への動物搬入に伴う検疫時におきたStaphylococcus xylosusによる病変

4. Survival of Common Marmoset (Callithrix jacchus jacchus)

5. 老化促進モデルマウスSAMP1系統における被毛と皮膚の加齢変化

6. 遺伝子改変技術を用いて作成した新たな癌悪液質モデルマウスの解析

7. セラミド細胞内選別輸送タンパク質 (Ceramide transfer protein; CERT)欠損マウスの作製


4. Survival of Common Marmoset (Callithrix jacchus jacchus)
 

Shin TANAKA1, Masashi TSUJIO1, Ryoichi SAITO2
1Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG), 2Clea Japan)

The survival of common marmoset (Callithrix jacchus jacchus) had been investigated. A total of 126 males and 165 females come from a breeding colony of Clea Japan, Tokyo were used. The average survival of males was 94.2 months of age (M), while was 67.4 M in females and was significantly (P<0.01) shorter than that in males. However, the longest survival was 259.9 M in males and 262.5 M in females. The 50% survival was 104.1 M in the male and 41.4 M in the female. The difference between the sexes seemed to become small with aging. The acute decrease of survival to 60% in males and to 40% in females around 30M might be explained in part by the loss on the sexual maturity and the first pregnancy. This may be due to an early coupling. This will reflect to the future planning of the reproduction. A 734C female, which recorded the longest survival, gave 34 times of deliveries until 201.7 M with 366C male and gave birth to 72 babies, and 64 of them including artificially nursed individuals were able to wean.

Key words: aging parameter, common marmoset, sex difference, survival

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