名古屋市立大学大学院医学研究科
生体情報・機能制御医学専攻・病態医科学講座  

Publication


・ Yamazaki S*, Odanaka M, Nishioka A, Kasuya S, Shime H, Hemmi H, Imai M, Riethmacher D, Kaisho T, Ohkura N, Sakaguchi S, Morita A. Ultraviolet B-Induced Maturation of CD11b-Type Langerin- Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin.JImmunol. 2018 Jan 1; 200 (1):119-129. *Corresponding author

・ Kubo R, Muramatsu S, Sagawa Y, Saito C, Kasuya S, Nishioka A, Nishida E, Yamazaki S, Morita A.  Bath-PUVA therapy improves impaired resting regulatory T cells and increases activated regulatory T cells in psoriasis. J Dermatol Sci. 2017 Apr;86(1):46-53

・ Gunawan M, Venkatesan N, Loh JT, Wong JF, Berger H, Neo WH, Li LY, La Win MK, Yau YH, Guo T, See PC, Yamazaki S, Chin KC, Gingras AR, Shochat SG, Ng LG, Sze SK, Ginhoux F, Su IH.  The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin. Nat Immunol. 2015 May;16(5):505-16.

・ Yamazaki S*, Nishioka A, KasuyaS, Ohkura N, Hemmi H, Kaisho T, Taguchi O, Sakaguchi S, Morita A. Homeostasisof thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.J Immunol. 2014 Dec 1;193(11):5488-97. *Corresponding author

・ Ito Y, Hashimoto M, Hirota K,Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N,Sakaguchi S. Detection of T cell responses to a ubiquitous cellular protein inautoimmune disease. Science. 2014 Oct 17;346(6207):363-8.

・ Yamazaki S*, Morita A. Dendritic cells in the periphery controlantigen-specific Natural and Induced regulatory T cells.Frontier Immunol2013;4: Article151, 1-13. *Correspondingauthor.

・ Yamazaki S*,
Maruyama A, Okada K, Matsumoto M, Morita A, Seya T Dendritic cells from oral cavity induce Foxp3+ regulatory T cells upon antigen stimulation.PLos One 2012; 7: e51665 *Corresponding author.

・ Yamazaki S*
, Okada K, Maruyama A, Matsumoto M, Yagita H, Seya T. TLR2-dependent induction of IL-10 and Foxp3+CD25+CD4+ regulatory T cells prevents effective anti- tumor immunity induced by Pam2 lipopeptides in vivo.PLos One 2011;6:e18833. *Correspondingauthor

・ Yamazaki S*
, Steinman RM. Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells.J Dermatol Sci 54,69-75,2009. *Corresponding author

・ Yamazaki S*,
Dudziak D, Heidkamp GF, Fiorese C, Bonito AJ, Inaba K, Nussenzweig MC, Steinman RM. CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells.J Immunol 181: 6923-6933, 2008. *Corresponding author

・ Yamazaki S*
, Bonito AJ, Spisek R, Dhodapkar M, Inaba K, Steinman RM.  Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+CD4+ regulatory T cells from peripheral Foxp3- precursors. Blood 110:4293-4302,2007. *Corresponding author

・ Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC. Differential antigen processing by dendritic cell subsets in vivo. Science 315:107-11,2007.

・ Yamazaki S, Patel M, Harper A, Bonito A, Fukuyama H, Pack M, Tarbell KV, Talmor M, Ravetch JV, Inaba, K, Steinman RM.  Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction.Proc Natl Acad Sci  USA 103: 2758-2763, 2006.

・ Yamazaki S*, Inaba K, Tarbell KV, Steinman RM.  Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. Immunol Rev 212:314-329, 2006. * Corresponding author

・ Ko K, Yamazaki S, Nakamura K, Nishioka T, Hirota K, Yamaguchi T, Shimizu J, Nomura T, Chiba T, Sakaguchi S. Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. J Exp Med  202:885-891, 2005.

・ Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM.  CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp  Med  199:1467-1477,2004.

・ Yagi H, Nomura T, Nakamura K, Yamazaki S, Kitawaki T, Hori S, Maeda M, Onodera M, Uchiyama T, Fujii S, Sakaguchi S. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells.Int Immunol16:1643-56, 2004.

・ Yamazaki S, Iyoda T, Tarbell K, Olson K, Velinzon K, Inaba K, Steinman RM. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen processing dendritic cells. J Exp Med  198:235-247, 2003.

・ Shimizu, J*, Yamazaki S*, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25+CD4+  regulatory T cells through GITR breaks immunological self-tolerance.Nat Immunol  3:135-142, 2002. *Equally contributed first author

・ Shimizu J, Yamazaki S, Sakaguchi S. Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity. J Immunol163:5211 5218,1999.