Yuan Gao, Yang Sun, Sadequl Islam, Tomohisa Nakamura, Taisuke Tomita, Kun Zou*, Makoto Michikawa*.
Presenilin 1 deficiency impairs Aβ42-to-Aβ40- and angiotensin-converting activities of ACE.
Frontiers in Aging Neuroscience , in press.

Sun Y, Gao Y, Islam S, Nakamura T, Zou K, and Michikawa M.
Apolipoprotein E4 inhibits γ-secretase activity via binding to γ-secretase complex.
J Neurochem , in press (https://doi.org/10.1111/jnc.15750)

Tomohisa Nakamura, Tadahiro Hashita, Chen Yuxin,Yuan Gao, Yang Sun, Sadequl Islam, Hiroyuki Sato, Yasuyuki Shibuya, Kun Zou, Tamihide Matsunaga, and Makoto Michikawa.
Ab42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood-brain barrier model.
Mol Brain , 16:15, 2023.

Honda K, Saito Y, Saito H, Toyoda M, Abe R, Saito T, Saido TC, Michikawa M, Taru H, Sobu Y, Hata S, Nakaya T, Suzuki T.
Accumulation of amyloid-β in the brain of mouse models of Alzheimer’s disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Neurobiology of Aging , 123: 63-74, 2023

Sheikh AM, Haque A, P Omori N, Yano S, Osago H, Mitaki S, Azad AK, Sakai H, Michikawa M, Nagai A.
Analysis of the time-dependent changes of phospholipids in the brain regions of a mouse model of Alzheimer’s disease.
Brain Res , 1800, 148197, 2023.

 

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Ohno K, Abdelhamid M, Zhou C, Jung C-G and Michikawa M.
Bifidobacterium brave MCC1274 supplementation increased the plasma levels of metabolites with potential anti-oxidative activity in APP Knock-in mice.
J Alzheimers Dis , 89: 1413-1425, 2022.

Taslima F, Abdelhamid M, Zhou C, Chen Y, Jung C-G, Michikawa M.
Tooth loss induces memory impairment and glial activation in young wild-type mice.
J Alzheier’s Dis Rep , 6(1): 663-675, 2022.

Mona Abdelhamid, Chunyu Zhou, Cha-Gyun Jung and Makoto Michikawa.
Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer’s Disease-related Pathologies in Wild-type Mice.
Nutrients , 19;14 (12):2543, 2022.

Sadequl Islam, Yang Sun, Yuan Gao, Tomohisa Nakamura, Arshad Ali Noorani, Tong Li, Philip C Wong, Noriyuki Kimura, Etsuro Matsubara, Kensaku Kasuga, Takeshi Ikeuchi, Taisuke Tomita, Kun Zou, and Makoto Michikawa
Presenilin is essential for ApoE secretion, a novel role of presenilin involved in Alzheimer’s disease pathogenesis.
J Neurosci , 23 February, 42 (8) 1574-1586, 2022

Abdelhamid M, Zhou C, Ohno K, Kuhara T, Jung C-G, Michikawa M.
Probiotic Bifidobacterium breve decreases Ab production via the upregulation of ADAM10 level and attenuates microglia activation I APP knock-in mouse model of Alzhiemer’s disease.
J Alzheimer's Dis , 85(4):1555-1571, 2022.

Jung C-G, Zhou C, Abdelhamid M, Shaaban E, Yamashita H, Michikawa M.
Sustained high body temperature exacerbates cognitive function and Alzheimer’s disease-related pathologies.
Sci Rep , Jul 18;12(1):12273, 2022

Zhou C, Jung C-G, Kim M-J, Watanabe A, Abdelhamid M, Taslima F, Michikawa M.
Insulin deficiency increases Sirt2 level in streptozotocin-treated Alzheimer’s disease-like mouse model: Increased Sirt2 induces tau phosphorylation through ERK activation.
Mol Neurobiol , in press.

Zou K, Islam S, Sun Y, Gao Y, Nakamura T, and Michikawa M.
Presenilin deficiency increases susceptibility to oxidative damage.
Frontiers in Aging Neuroscience , in press.

 

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Abdullah, M., Nakamura, T., Ferdous, T. Gao, Y., Chen, Y., Zou, K., Michikawa M.
Cholesterol Regulates Exosome Release in Cultured Astrocytes.
Front Immunol, 12: 722581, 2021

Azad A. K., Sheikh A.M., Haque M. A., Osago H., Sakai H., Shibly A. Z., Yano S., Michikawa M., Hossain S., Tabassum S., Garu A., Zhou X., Zhang Y., Nagai A.
Time-dependent analysis of plasminogens in the hippocampus of an Alzheimer’s disease mouse model: A role of ethanolamine plasminogen.
Brain Sci, 11: 1603, 2021

Tsushima, H., Yamada, K., Miyazawa, D., Ohkubo, T., Michikawa M., Abe-Dohmae, S.
Comparison of the Physical Characteristics and Behavior in ABC Transporter A1, A7 or Apolipoprotein E Knockout Mice with Lipid Transport Dysfunction.
Biol Pharm Bull, 44: 1851-1859, 2021

Nakamura T, Zou K, Shibuya Y, Michikawa M.
Oral dysfunctions and cognitive impairment/dementia.
J Neurosci Res , 99(2), 518-528, 2021. doi:10.1002/jnr.24745

Taslima F, Jung C-G, Zhou C, Abdullah M, Abdelhamid M, Saito T, Saido T. C., Michikawa, M.
Tooth loss iduces memory impairment and gliosis in App knock-in mouse models of Alzheiemr’s disease.
J Alzheimers Dis , 980( 4): 1687-1704, 2021. doi: 10.3233/JAD-201055

Sugimoto T, Sakurai T, Akatsu H, Doi T, Fujiwara Y, Hirakawa A, Kinoshita F, Kuzuya M, Lee S, Matsuo K, Michikawa M, Ogawa S, Otsuka R, Sato K, Shimada H, Suzuki H, Suzuki H, Takechi H, Takeda S, Umegaki H, Wakayama S, Arai H. The Japan-multimodal intervention trial for prevention of dementia (J-MINT): the study protocol for an 18-month, multicenter, randomized, controlled trial.
J Prev Alz Dis , in press.

 

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Noorani A.A, Yamashita H, Gao Y, Islam S; Su Y, Nakamura T, Enomoto H, Zou K, Michikawa M.
High temperature promotes amyloid β-protein production and γ-secretase complex formation via Hsp90.
J Biol Chem , 295(52), 18010-18022, 2020. doi:10.1074/jbc.RA120.013845

Kun Zou, Mohammad Abdullah, Makoto Michikawa.
Current Biomarkers for Alzheimer’s Disease: From CSF to Blood.
J Personalized Med, 10(3), 2020. doi:10.3390/jpm10030085

Tetsuya Goto, Eriko Kuramoto, Ashis Dhar, Rachel P.-H. Wang, Haruka Seki, Haruki Iwai, Atsushi Yamanaka, Shin-Ei Matsumoto, Hiromitsu Hara, Makoto Michikawa, Yasumasa Ohyagi, Wai K. Leung, Raymond C.-C. Chang. Neurodegeneration of Trigeminal Mesencephalic Neurons by the Tooth Loss Triggers the Progression of Alzheimer’s Disease in 3×Tg-AD Model Mice.
J Alzheimers Dis, 76(4), 1443-1459, 2020. doi:10.3233/JAD-200257

Abdelhamid, M., Jung, C. G., Zhou, C., Abdullah, M., Nakano, M., Wakabayashi, H., Abe, F., Michikawa M.
Dietary Lactoferrin Supplementation Prevents Memory Impairment and Reduces Amyloid-beta Generation in J20 Mice
J Alzheimers Dis, 74: 245-259, 2020. doi:10.3233/JAD-191181

Tabassum S, Sheikh A. M., Yano S, Ikeue T, Mitaki S, Michikawa M and Nagai A. A cationic gallium phthalocyanine inhibits amyloid β peptide fibril formation.
Curr Alzheimer Res. 17: 1-12, 2020. doi:10.2174/1567205017666201008112002

Zhou C, Taslima T, Abdelhamid M, Kim S-W, Akatsu H, Michikawa M, Jung C-G. Beta-amyloid increases the expression levels of Tid1 responsible for neuronal cell death and amyloid beta production.
Mol Neurobiol, 57 (2): 1099 - 1114 ,2020.

Yu Fujita, Tomoji Maeda, Chiharu Sato, Masaya Sato, Hatsune Hatakeyama, Yume Ota, Nozomi Iwabuchi, Komaki Tatesawa, Ayako Nomura, Kun Zou, Hiroto Komano. Engulfment of Toxic Amyloid β-protein in Neurons and Astrocytes Mediated by MEGF10.
Neuroscience, 443 :1 - 7, 2020.

Kota Kikuchi, Yu Fujita, Xuefeng Shen, Junjun Liu, Tomoki Terakawa, Daiki Nishikata, Sho Niibori, Takayuki Ito, Kazuyuki Ashidate, Takuya Kikuchi, Yu Kikuchi, Tomoji Maeda, Kun Zou, Hiroto Komano. Interaction between Angiotensin Receptor and β-Adrenergic Receptor Regulates the Production of Amyloid β-Protein.
Biological Pharmaceutical Bulletin, 43 (4): 731 - 735, 2020.

 

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Mohammad Abdullah, Noriyuki Kimura, Hiroyasu Akatsu, Yoshio Hashizume, Taslima Ferdous, Takuto Tachita, Shinsuke Iida, Kun Zou, Etsuro Matsubara, Makoto Michikawa.
Flotillin is a Novel Diagnostic Blood Marker of Alzheimer’s Disease.
J Alzheimers Dis, 72 (4): 1165 - 1176, 2019.

Shuyu Liu, Fujiko Ando, Yu Fujita, Junjun Liu, Tomoji Maeda, Xuefeng Shen, Kota Kikuchi, Aoi Matsumoto, Mirai Yokomori, Chiaki Tanabe-Fujimura, Hiroshi Shimokata, Makoto Michikawa, Hiroto Komano, Kun Zou. A clinical dose of angiotensin-converting enzyme (ACE) inhibitor and heterozygous ACE deletion exacerbate Alzheimer's disease pathology in mice.
J Biol Chem, 294 (25): 9760 - 9770, 2019.

Shen X, Liu J, Fujita Y, Liu S, Maeda T, Kikuchi K, Obara T, Takebe A, Sayama R, Takahashi T, Matsue A, Sera K, Michikawa M, Komano H, Zou K. Iron treatment inhibits Aβ42 deposition in vivo and reduces Aβ42/Aβ40 ratio.
Biochem Biophys Res Comm ,512 (4): 653 - 658, 2019.

Ano Y, Yoshikawa M, Takaichi Y, Michikawa M, Uchida K, Nakayama H, Takashima A.
Iso-α-Acids, Bitter Components in Beer, Suppress Inflammatory Responses and Attenuate Neural Hyperactivation in the Hippocampus.
Front Pharmacol, 10:81, 2019.

 

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Higaki S, Muramatsu M, Matsuda A, Matsumoto K, Satoh J, Michikawa, M, Niida S. Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models.
PloS One, 13: (5): e0196929, 2018

Ogawa, T., Okihara, H., Kokai, S., Abe, Y., Karin H., Uchima K., Makiguchi, M., Kato, C., Yabushita, T., Michikawa, M., Ono, T. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone level.
J Neurosci Res, 96(6):1056-1065, 2018

Hosihkawa M, Yokoyama S, Hisa H, Michikawa, M, Ito J-I.
FGF2 enhances generation of ApoE-containng HDL along with FGF1 in rat astrocytes under oxidative stress.
J Brain and Neurosci Res, 2: 002, 2018.

Yoshikawa, M. Soeda, Y., Michikawa, M., Almeida, O. F. X., Takashima, A.
Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.
Front Neurosci, 12: 124, 2018.

Ogawa, Takuya; Okihara, Hidemasa; Kokai, Satoshi; Abe, Yasunori; Karin Harumi, UchimaKoecklin; Makiguchi, Mio; Kato, Chiho; Yabushita, Tadachika; Michikawa, Makoto, Ono, Takashi.
Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone level.
J Neurosci Res, 96(6):1056-1065, 2018

 

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ZuiZhanga, Yoshiko Takeda-Uchimuraa, TahminaFoyeza, ShioriOhtake-Niimia, Narentuyaa, Hiroyasu Akatsu,KazuchikaNishitsuji, Makoto Michikawa, Tony Wyss-Coray, Kenji Kadomatsu, and Kenji Uchimura.
Deficiency of a sulfotransferase for sialic acidmodifiedglycans mitigates Alzheimer’s pathology.
Proc Natl AcadSci USA, 114(14): E2947-E2954, 2017

Yosuke Takeda, Hiroshi Oue, Shinsuke Okada, Akira Kawano, KatsunoriKoretake, Makoto Michikawa, YasumasaAkagawa and Kazuhiro Tsuga. Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain derived neurotrophic factor in the hippocampus of adult mice.
BMC Neurosci, 17:81, 2017
Naoyuki Ishida, Yuichi Ishihara, Kazuto Ishida, Hiroyuki Tada, Yoshiko Funaki-Kato, Makoto Hagiwara, Taslima Ferdous, Mohammad Abdullah, Akio Mitani, Makoto Michikawa, Kenji Matsushita
Periodontitis induced by bacterial infection exacerbates features of Alzheimer's disease in transgenic mice.
npj Aging Mech Dis, 3: 15, 2017.

 

ZuiZhanga, Yoshiko Takeda-Uchimuraa, TahminaFoyeza, ShioriOhtake-Niimia, Narentuyaa, Hiroyasu Akatsu,KazuchikaNishitsuji, Makoto Michikawa, Tony Wyss-Coray, Kenji Kadomatsu, and Kenji Uchimura.

Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer’s pathology.

Proc Natl AcadSci USA, 2017

 

Naoyuki Ishida, Yuichi Ishihara, Kazuto Ishida, Hiroyuki Tada, Yoshiko Funaki-Kato, Makoto Hagiwara, Taslima Ferdous, Mohammad Abdullah, Akio Mitani, Makoto Michikawa, Kenji Matsushita

Periodontitis induced by bacterial infection exacerbates features of Alzheimer's disease in transgenic mice.

Aging Mech Dis, in press

 

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Yosuke Takeda, Hiroshi Oue, Shinsuke Okada, Akira Kawano, Katsunori Koretake, Makoto Michikawa, Yasumasa Akagawa, Kazuhiro Tsuga

Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice.

BMC Neurosci, 17: 81, 2016

 

Nunome M, Enomoto H, Abdullah M, Gong JS, Jung CG, Kamijima M, Michikawa M.

Effects of overexpression of lipoprotein lipase (LPL) on Aβ burden and memory function in LPL and APP-double-transgenic mice.

J System Integr Neurosci, in press.

 

Ko M, Hattori T, Abdullah M, Gong JS, Yamane T, Michikawa M.

Phosphatidylcholine protects neurons from toxic effects of amyloid beta-protein in culture.

Brain Res, 1642: 376-383, 2016.

 

Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, and Matsuo M.

ABCG1 and ABCG4 suppress g-secretase activity and amyloid β production.

PLOS ONE, 11(5): e0155400, 2016.

 

Abdullah M, Takase H, Nunome M, Enomoto H, Ito J-I, Gong J-S, and Michikawa M.

Aβ reduces exosome release from astrocytes by enhancing JNK phosphorylation.

J Alzhiemer Dis, 53: 1433-1441, 2016.

 

Gong J-S, Abdullah M, Nunome M, Enomoto H, Ito J, and Michikawa M.

Memantine prevents Aβ-induced neuronal death in vitro.

Glob Vaccines Immunol, 1(1): 14-18, 2016

 

Oue, H, Miyamoto, Y, Koretake, K, Okada, S, Doi, K, Jung, C.-G, Michikawa, M. Akagawa, Y.

Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse.

Gerodontology 33(3): 308-14, 2016.

 

Fuwa, D, Fukuda, M, Ogiyama, Y, Sato, R, Mizuno, M, Miura, T, Abe-Dohmae,Michikawa, M, Kobori, H, Ohte, N.

Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease.

J Renin Angiotensin Aldosterone Syst, 2016, 2016 Jun 9;17(2)

 

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Liu J, Liu S, Matsumoto Y, Murakami S, Sugakawa Y, Kami A, Tanabe C, Maeda T, Michikawa M, Komano H.

Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology.

Sci Rep. 2015 Jul 8;5:12059.

 

Hosono T, Mouri A, Nishitsuji K, Jung C-G, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabeshima T, Michikawa M.

Arachidonic or docosahezanenoic acid diet prevents memory impairment in Tg2576 mice.

J Alzheimers Dis.,48(1): 149-162, 2015

 

Hosono T, Nishitsuji K, Nakamura T, Jung C-G, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M.

Arachidonic Acid Diet Attenuates Aβ Deposition in Tg2576 Mice.

Brain Res, 1613: 92-99, 2015.

 

Ito J, Nagayasu Y, Ogawa T, Okihara H, Michikawa M.

Biochemical properties in membrane of rat astrocytes under oxidative stress.

Brain Res, 1615: 1-11, 2015.

 

Md.Sheikh, Michikawa M, Kim S-U, Nagai A.

Lysophosphatidylcholine increases the neurotoxicity of Alzheimer’s amyloid β1-42 peptide: Role of oligomer formation.

Neuroscience, 292: 159-69, 2015.

 

Ohm K-O, Kim M-J, Kawqaguchi M, Akatsu H, Miura Y, Misumi S, Hida H, Choi E-K, Kim Y-S, Michikawa M, Jung C-G.

ATBF1 is a novel amyloid precursor binding protein that affects amyloid β production.

J Alzheimers Dis, 43: 243-57, 2015.

 

Jung C-G., Ohm K-O, Horike H, Kim M-J, Misumi S, Ishida A, Ueda Y, Choi E-K, Kim Y-S, Michikawa M, Hida H.

Auraptene increases the production of amyloid-beta via c-Jun N-terminal kinase -dependent activation of γ-secretase.

J Alzheimers Dis, 43: 1215-28, 2015.

 

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Okihara H, Ito J, Kokai S, Ishida T, Hiranuma M, Kato C, Yabushita T, Ishida K, Ono T, Michikawa M.

Liquid diet induces memory impairment accompanied by a decreased number of hippocampal neurons in mice.

J Neurosci Res. 92(8):1010-7 2014

 

Ito JI, Nagayasu Y, Miura Y, Yokoyama S, Michikawa M.

Astrocytes endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA1.

Brain Res. 27;1570:1-12. 2014

 

Nagayasu Y, Morita S, Hayashi H, Miura Y, Yokoyama K, Michikawa M, Ito J.

Incresing cellular level of phosphatidic acid enhances FGF-1 production in long-term cultured rat astrocytes.

Brain Res, 1563:31-40, 2014.

 

Kheirollah A, Nagayasu Y, Ueda H, Yokoyama S, Michikawa M, Ito J.

Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes.

J Neurosci Res, 92(4):455-463, 2014.

 

Hoshino　H, Foyez T, Ohtake-Niimi S, Takeda-Uchimura Y, Michikawa M, Kadomatsu K and Uchimura K

KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain

J Histochem Cytochem, 62(2), 145-56, 2014.

 

 

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Oue H, Miyamoto Y, Okada S, Koretake K, Jung CG, Michikawa, M, Akagawa, Y.

Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice.

Behav Brain Res 252: 318-325, 2013

 

Zou K, Liu J, Watanabe A, Hiraga S, Liu S, Tanabe C, Maeda T, Terayama Y, Takahashi S, Michikawa M, Komano H.

Aβ43 is the earliest depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE

Am J Pathol, 182: 2322-2331, 2013

 

Ito J, Nagayasu Y, Hoshikawa M, Kato K.H., Miura Y, Asai K, Hayashi H, Yokoyama Y, Michikawa M.

Enhancement of FGF-1 release along with cytosolic proteins from rat astrocytes by hydrogen peroxide

Brain Res., 1552: 12-21, 2013

 

Ito J, Gong J, Michikawa M. 

Oxidative Stress and FGF-1 release from Astrocytes.

J Alzheimer's Dis Parkinsonism, 2013, 3.5

 

 

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Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Akatsu H, Hossain M, Nishitsuji K, van Kuppevelt, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K.

Heparan sulfate subdomains that are degraded by sulf accumulate in cerebral amyloid β plaques of Alzheimer's disease : Evidence from mouse models and patients.

Am J Pathol, 180(5): 2056-2067, 2012.

 

Yasuno F, Tanimukai S, Sasaki M, Hidaka S, Ikejima C, Yamashita F, Kodama C, Mizukami K, Michikawa M, Asada T.

Association between cognitive function and plasma lipids of the elderly after controlling for apolipoprotein E genotype.

Am. J. Geriat. Psychiat. 20(7): 574-583, 2012

 

 

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Nishitsuji K, Hosono T, Uchimura K, Michikawa M.

Lipoprotein lipase is a novel A beta -binding protein that promotes glycosaminoglycan- dependent cellular uptake of A in astrocytes.

J. Biol. Chem. 286: 6393-6401, 2011.

 

Nishitsuji K, Hosono T, Nakamura T, Bu G, Michikawa M.

Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain-barrier

model.

J. Biol. Chem. 286(20): 17536-17542, 2011.

 

Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M,

Michikawa M, Matsubara E.

The dissociation of Aβ from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates Aβ42 assembly.

J. Neurosci. Res. 6: 815-821, 2011

 

Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Shoji M, Yanagisawa K,

Michikawa M, Matsubara E.

Extracellular and intraneuronal HMW-A oligomers represent a molecular basis of memory loss in Alzheimer's disease model mouse.

Mol. Neurodegener. 2011; 6: 20.

 

Akatsu H, Ogawa N, Kanesaka T, Hori A, Yamamoto T, Matsukawa N, Michikawa M.

Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease.

J. Neurol. Sci. 2011; 300: 67-73.

 

Marutani T, Maeda T, Tanabe C, Zou K, Araki W, Kokame K, Michikawa M, Komano H.

ER-stress-inducible Herp, facilitates the degradation f immature nicastrin.

Biochim. Biophys. Acta. 1810: 790-8, 2011.

 

Hosono-Fukao T, Ohtake-Niimi S, Nishitsuji K, Hossain M, van Kuppevelt TH, Michikawa M, Uchimura K.

RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature.

J. Neurosci. Res., 89: 1840-8 ,2011.

 

Jung C-G, Uhm K-O, Miura Y, Hosono T, Horike H, Khanna K K, Michikawa M.

Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons.

Mol Neurodegener, 6: 47, 2011.

 

 

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Minagawa H, Watanabe A, Akatsu H, Adachi K, Ohtsuka C, Terayama Y, Hosono T, Takahashi S, Wakita H, Jung C-G, Komano H,

Michikawa M.

Homocysteine, another risk factor for Alzheimer's disease, impairs apolipoprotein E3 function.

J. Biol. Chem. 2010; 285:38382-38388.

 

Jung C-G, Horike H, Cha B-Y, Uhm K-O, Yamauchi R, Yamaguchi T, Hosono T, Iida K, Woo J-T, Michikawa M.

Honokiol increases ABCA1 expression level by activating retinoid X receptor β.

Biol. Pharm. Bull, 2010; 33:1105-1111.