Table 1:
Malignant masses (74 patients, 74 masses)
Histopathology |
Cases |
Mean RI |
RI range |
Serous Cystadenocarcinoma |
28 |
0.47 |
0.29-0.71 |
Mucinous Cystadenocarcinoma |
4 |
0.58 |
0.29-0.87 |
Endometrial Carcinoma |
6 |
0.52 |
0.47-0.67 |
Clear cell Carcinoma |
2 |
0.43 |
0.41-0.45 |
Mixed Epithelial Carcinoma |
4 |
0.51 |
0.32-0.71 |
Indifferentiated Epithelial Carcinoma |
6 |
0.45 |
0.33-0.55 |
Mixed M_llerian Tumor |
2 |
0.44 |
0.40-0.48 |
Immature Teratoma |
2 |
0.36 |
0.22-0.44 |
Dysgerminoma |
6 |
0.4 |
0.33-0.55 |
Granulosa cell Tumor |
14 |
0.36 |
0.22-0.44 |
Table 2:
Bening masses (120 patients, 120 masses)
Histopathology |
Cases |
Mean RI |
RI range |
Fibroma |
10 |
0.55 |
0.36-0.73 |
Thecoma |
4 |
0.52 |
0.35-0.69 |
Mature Cystic Teratoma |
14 |
0.81 |
0.58-1.0 |
Endometrioma |
14 |
0.66 |
0.43-1.0 |
Serous Cystadenoma |
24 |
0.86 |
0.63-1.0 |
Mucinous Cystadenoma |
18 |
0.85 |
0.58-1.0 |
Follicular Cyst |
14 |
0.86 |
0.70-1.0 |
Corpus Luteum Cyst |
12 |
0.63 |
0.38-0.93 |
Tuboovarian Abscess |
8 |
0.70 |
0.56-1.0 |
Paraovarian Abscess |
2 |
0.96 |
0.90-0.98 |
Sensitivity, specifity, PPV, NPV, accuracy rate and p values for predicting malignancy at cut off values 0.3-0.7 are shown at table 3.
Cut off Value |
Sensitivity |
Specifity |
PPV |
NPV |
Accuracy Rate |
P value |
0.3 |
8.1 |
100 |
100 |
63.8 |
64.9 |
>0.05 |
0.35 |
18.9 |
100 |
100 |
66.7 |
69.1 |
<0.001 |
0.40 |
35.1 |
95 |
81.2 |
70.4 |
72.2 |
<0.001 |
0.45 |
56.8 |
91.7 |
80.8 |
77.5 |
78.4 |
<0.001 |
0.50 |
70.3 |
90 |
81.3 |
83.1 |
82.5 |
<0.001 |
0.55 |
75.7 |
85 |
75.7 |
85 |
81.5 |
<0.001 |
0.60 |
89.2 |
78.2 |
71.7 |
92.2 |
82.5 |
<0.001 |
0.65 |
89.2 |
75 |
68.8 |
91.8 |
80.4 |
<0.001 |
0.70 |
91.9 |
68.3 |
64.2 |
93.2 |
77.3 |
<0.001 |
The relationship between stages and mean doppler RI according to different types of tumors are shown at table 4.
Histopathology |
Stagel (n--20) |
Stage2 (n-- 1 2) |
Stage3 (n7-37) |
Stage4 (n=4) |
Serous cyst adenocarcinoma |
1 |
5 |
20 |
2 |
Mucinous cyst adenocarcinoma |
- |
2 |
- |
2 |
Endometrioid adenocarcinoma |
- |
6 |
- |
- |
Clear cell carcinoma |
- |
- |
2 |
- |
Mixed epithelial carcinoma |
- |
- |
4 |
- |
Indifferentiated carcinoma |
1 |
- |
5 |
- |
Immature teratoma |
- |
- |
2 |
- |
Dysgerminoma |
2 |
- |
2 |
- |
Granulosa cell tumor |
14 |
- |
- |
- |
Mixed M_llerian tumor |
2 |
- |
- |
- |
Mean RI |
0,39±0,07 |
0,55±0,18 |
0,47±0,12 |
0,35±0,08 |
Mean RI for stage 2 was significantly different from stage1 and stage 4. The relationship between grades and mean doppler RI according to different types of tumors are shown at table 5.
Histopathology |
Grade I N(I 5) |
Grade 2 N(40) |
Grade 3 N(52) |
Undifferentiated N(3) |
Serous cyst adenocarcinoma |
10 |
18 |
30 |
- |
Mucinous cyst adenocarcinoma |
3 |
12 |
13 |
- |
Endometrioid adenocarcinoma |
- |
1 |
2 |
- |
Clear cell carcinoma |
- |
3 |
2 |
- |
Undifferentiated carcinoma |
- |
- |
- |
3 |
Dysgerminoma |
- |
- |
- |
- |
Endodermal sinus tumor |
- |
1 |
- |
- |
Immature teratoma |
1 |
- |
- |
- |
Malignant lymphoma |
- |
1 |
- |
- |
Granulosa cell tumor |
1 |
2 |
1 |
- |
Epidermoid carcinoma |
- |
- |
1 |
- |
Malignant mixed m_llerian tumor |
- |
- |
1 |
- |
Metastatic disease |
- |
2 |
2 |
- |
Mean RI |
0,39±0,05 |
0,45±0,11 |
0,49±0,13 |
0,41±0,12 |
Medical School |