1996

Isobe, I., Watanabe, T., Yotsuyanagi, T., Hazemoto, N., Yamagata, K., Ueki, T., Nakanishi, K., Asai, K., Kato, T. Astorocytic contribution to blood-brain barrier (BBB) formation by endothelial cells: a possible use of aortic endothelial cell for in vitro BBB model. Neurochem. Int. 28(1996)523-533

Matsukawa, K., Moriyama, A., Kawai, Y., Asai, K., Kato, T. Tissue distribution of human gliostatin/platelet-derived endothelial cell growth factor (PD-ECGF) and its drug-induced expression. Biochim. Biophys. Acta 1314(1996)71-82

Fuse, T., Yamada, K., Asai, K., Kato, T., Nakanishi, M. Heat shock-mediated cell cycle arrest is accompanied by induciton of p21 CK1. Biochem. Biophys. Res. Commun. 225(1996)759-763

Yonezawa, M., Otsuka, T., Matsui, N., Tsuji, H., Kato, K., Moriyama, A and Kato, T. Hyperthermia induces apoptosis in malignant fibrous histiocytoma cells in vitro. Int. J. Cancer 66(1996)347-351

Kasugai, K., Joh, T., Kato, T. and Itoh, M. Effects of the anti-gastric secretory drugs IT-066 and omeprazole on mitogenic activities in the gastric juice of the rat. Scand. J. Gastroenterol. 31(1996) 112-117

Kageyama, T., Moriyama, A., Kato, T., Sano, M. and Yonezawa, S. Determination of cathepsins D and E in various tissues and cells of rat, monkey, and man by the assay with b-endorphin and substance P as substrates. Zoological Science 13(1996)693-698

Toyama, T., Iwase, H., Yamashita, H., Iwata, H., Yamashita, T., Ito, K., Hara, Y., Suchi, M., Kato, T., Nakamura, T. and Kobayashi, S. Microsatellite instability in sporadic human breast cancers. Int. J. Cancer 68(1996)447-451

Moriyama, A., Matsukawa, K., Matsubara, M. and Kato, T. Application of high- performance capillary electrophoresis to quantification of products of the reverse transcriptase-polymerase chain reaction. Annual Review 1(1996)55-58

1997

Mizuno, H., Uemura, K., Moriyama, A., Wada, Y., Asai, K., Kimura, S., Kato, T. Glucocorticoid induced the expression of mRNA and the secretion of lipocortin 1 in rat astrocytoma cells. Brain Res. 746(1997)256-268

Waguri, Y., Otsuka, T., Sugimura, I., Matsui, N., Asai, K., Moriyama, A., and Kato, T. Gliostatin/platelet-derived endothelial cell growth factor as a clinical marker of rheumatoid arthritis and its regulation in fibroblast-likes synoviocytes. Br. J. Rheumatol. 36(1997)315-321

Hashimoto, Y., Kohri, K., Hayashi, Y., Moriyama, A., Iguchi, M. Asai, K., and Kato, T. Specific detection of k light chain in uric acid stones. Life Sci. 61(1997)249-253
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Kasugai, K., Joh, T., Kataoka, H., Sasaki, M., Tada, T., Asai, K., Kato, T., Itoh, M. Evidence for participation of gliostatin/platelet-derived endothelial cell growth factor in gastric ulcer healing. Life Sci. 61(1997)1899-1906

Sano, H., Tada, T., Moriyama, A., Ogawa, H., Asai, K., Kawai, Y., Hodgson, M.E., Kato, T., Wada, Y., and Suchi, M. Isolation of a rat histidase cDNA sequence and expression in Escherichia coli-evidence of extrahepatic/epidermal distribution. Eer. J. Biochem. 250(1997)212-221

Takahashi, M., Yamada, T., Nakanishi, K., Fujita, K., Nakajima, K., Nobusawa, E., Yamamoto, T., Kato, T., and Okada, H. Influenza a virus infection of primary cultured cells from rat fetal brain. Parkinsonism & Related Disorders 3 (1997)97-102

Yamagata, K., Tagami, M., Nara, Y., Fujino, H., Kubota, A., Numano, F., Kato, T. and Yamori, Y. Faulty induction of blood-brain barrier functions by astrocytes isolated from stroke-prone spontaneously hypertensive rats. Clinical and Experimental Pharmacology and Physiology 24(1997)686-691

Yamagata, K., Tagami, M., Nara, Y., Mitani, M., Kubota, A., Fujino, H., Numano, F., Kato, T. and Yamori, Y. Astrocyte-conditioned medium induces blood-brain barrier properties in endothelial cells. Clinical and Experimental Pharmacology and Physiology 24 (1997)710-713

Kataoka, H., Joh, T., Kasugai, K., Kato, T., and Moriyama, A. Mitogenic properties of human gastric juice. Digestive Diseaes and Sciences 42(1997)1747-1754

1998

Asai, K., Ishii, A., Yao, L., Diamond, I., and Gordon, S.A. Varying effects of ethanol on transfected cell lines. Alcohol. Clin. Exp. Res. 22(1998)163-166

Asai, K., Fujita, K., Yamamoto, M., Hotta, T., Morikawa, M., Kokubo, M., Moriyama, A., Kato, T. Isolation of novel human cDNA (hGMF-g) homologous to Glia Maturation Factor-b gene. Biochim. Biophys. Acta 1396(1998)242-244

Fujita, K., Nakanishi, K., Sobue, T., Ueki, T., Asai, K., Kato, T. Astrocytic gap junction blockage and neuronal Ca2+ oscillation in neuron-astrocyte cocultures in vitro. Neurochem. Int. 33(1998)41-49

Kataoka, H., Joh, T., Kasugai, K., Okayama, N., Moriyama, A., Asai, K., and Kato, T. Expression of mRNA for heregulin and its receptor, ErbB-3 and ErbB-4, in human upper gastrointestinal mucosa. Life Sci. 63(1998)553-564

Mizuno, H., Asai, K., Fujita, K., Uemura, K., Wada, Y., Moriyama, A., Ogawa, H., Kimura, S., Kato, T. Neurotrophic action of lipocortin 1 derived from astrocytes on cultured rat cortical neurons. Mol. Brain Res. 60(1998)28-39

Fuse,T., Yoon, K.W., Kato, T., Yamada, K. Heat-induced apoptosis in human glioblastoma cell line A172. Neurosurgery 42(1998)843-849

Harada, S., Komatsu, H., Seto, M., Ni.Jian-Hua, H., Hayami, Y., Tsuboi, K., Wakita, A., Nitta, M., Kato, T., Ueda, R. Microsatellite instability is rare in the clinical course of myelodysplastic syndrome studied with DNA from fresh and paraffin-embedded tissues. J. Cancer Res. Clin. Oncol. 124(1998)231-235

Hashimoto, Y., Kohri, K., Kaneko, Y., Morisaki, H., Kato, T., Ikeda, K., Nakanishi, M. Critical role for the 310 helix region of p57kip2 in cyclin-dependent kinase 2 inhibition and growth suppression. J. Biol. Chem. 273(1998)16544-16550

Ni, H., Nitta, M., Komatsu, H., Kojima, S., Suzuki, S., Harada, S., Tsuboi, K., Banno, S., Wakita, A., Yazaki, M., Ren, L., Kato, T., Ueda, R. Detection of bcr/ab1 fusion transcripts by semiquantitative multiplex RT-PCR combined with a colormetric assay in Ph positive leukemia. Cancer Letters 124(1998)173-180

Okayama, N., Itoh, M., Joh, T., Miyamoto, T., Takeuchi, T., Moriyama, A., and Kato, T. Regulatory mechanism of pepsinogen gene expression in monolayer cultured guinea pig gastric chief cells. Digestive Diseases and Sciences 43(1998)2744-2749

Mase, M., Yamada, K., Fujita, K., Nakanishi, K., Kato, T. Effect of chronic inhibition of NOS on functional synaptic formation in neuron-glia cultured of rat cortex. Restor. Neurol. Neurosci. 13(1998) 233-234

1999

Muro, H., Waguri-Nagaya, Y., Mukofujiwara, Y., Iwahashi, T., Otsuka, T., Matsui, N., Moriyama, A., Asai, K., Kato, T. Autocrine induction of gliostatin/platelet-derived endothelial cell growth factor (GLS/PD-ECGF) and GLS-induced expression of matrix metalloproteinases in rheumatoid arthritis synoviocytes. Rheumatology(Oxford) 38(1999)1195-1202

Sobue, K., Yamamoto, N., Yoneda, K., Hodgson, M.E., Yamashiro, K., Tsuruoka, N., Tsuda, T., Katsuya, H., Miura, Y., Asai, K., Kato, T. Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors. Neurosci. Res. 35(1999)155-164

Okada, Y., Takeyama, H., Sato, M., Morikawa, M., Sobue, K., Asai, K., Tada, T., Kato, T., and Manabe, T. Experimental implication of celiac ganglionotropic invasion of pancreatic-cancer cells bearing c-ret proto-oncogene with reference to glial-cell-line-derived neurotrophic factor (GDNF). Int. J. Cancer 81(1999)67-73

Katano, H., Fujita, K., Kato, T., Asai, K., Kawamura, Y., Masago, A., and Yamada, K. Traumatic injury in vitro induces IEG mRNAs in cultured glial cells, suppressed by co-culture with neurons. Neuroreport 10(1999)2439-2448

Sobue, K., Yamamoto, N., Yoneda, K., Fujita, K., Miura Y., Asai, K., Tsuda, T., Katsuya, H., Kato, T. Molecular cloning of two bovine aquaporin-4 cDNA isoforms and their expression in brain endothelial cells. Biochim. Biophys. Acta 1489(1999)393-398

Miura, Y., Wake, H., Kato, T. TBE, or not TBE; That is the question: Beneficial usage of tris-borate for obtaining a higher resolution of small DNA fragments by agarose gel electrophoresis. Nagoya Med. J. 43(1999)1-6

Hayami, Y., Komatsu, H., Iida, S., Utsunomiya, A., Hanada, S., Hua, XJ., Huiping, N., Harada, S., Tsuboi, K., Banno, S., Wakita, A., Kato, T., and Ueda, R. Microsatellite instability as a potential marker for poor prognosis in adult T cell leukemia/ lymphoma. Leukemia and Lymphoma 32(1999)345-349

Okada, Y., Suchi, M., Takeyama, H., Hodgson, M.E., Kato, T., and Manabe, T. Noncardiogenic pulmonary edema as the chief manifestation of a pheochromocytoma: A case report of MEN 2A with pedigree analysis of the RET proto-oncogene.Tohoku J. Exp. Med. 188(1999)177-187

2000

Zhang, L.Y., Ito, J., Kato, T. and Yokoyama, S. Cholesterol homeostasis in rat astrocytoma cells GA-1. J. Biochem. 128(2000)837-845

Waguri-Nagaya, Y., Otsuka, T., Sugimura, I., Matsui, N., Asai, K., Nakajima, K., Tada, T., Akiyama, S., and Kato, T. Synovial inflammation and hyperplasia induced by gliostatin/ platelet-derived endothelial cell growth factor in rabbit knees. Rheumatol. Int. 20(2000)13-19

Kataoka, H., Joh, T., Miura, Y., Tamaoki, T., Seno, K., Ohara, H., Nomura, T., Tada, T., Asai, K., Kato, T., and Itoh, M. AT motif binding factor 1-A (ATBF1-A) negatively regulates transcription of the aminopeptidase N gene in the crypt-villus axis of small intestine. Biochem. Biophys. Res. Commun. 267(2000)91-95

Hotta, T., Asai, K., Fujita, K., Kato, T., and Higashida, H. Membrane-bound form of ADP-ribosyl cyclase in rat cortrical astrocytes in culture. J. Neurochem. 74(2000)669-675

Tsuiki, H., Asai, K., Yamamoto, M., Fujita, K., Inoue, Y., Kawai, Y., Tada, T., Moriyama, A., Wada, Y., Kato, T. Cloning of a rat maturation factor-g_(rGMFG) cDNA and expression of its mRNA and protein in rat organs. J. Biochem. 127(2000)517-523

Fuse, T., Tanikawa, M., Nakanishi, M., Ikeda, K., Tada, T., Inagaki, H., Asai, K., Kato, T., and Yamada, K. p27Kip1 expression by contact inhibition as a prognostic index of human glioma. J. Neurochem. 74(2000)1393-1399

Goto, N., Maeyama, J., Yasuda, Y., Isaka, M., Matano, K., Kozuka, S., Taniguchi, T., Miura, Y., Ohkuma, K., Tochikubo, K. Safety evaluation of recombinant cholera toxin B subunit produced by Bacillus brevis as a mucosal adjuvant. Vaccine 18(2000)2164-2171

Sakata, N., Hemmi, K., Kawaguchi, M., Miura, Y., Noguchi, S., Ma, D., Sasahara, M., Kato, T., Hori, M., and Tamaoki, T. The mouse ZFH-4 protein contains four homeodomains and twenty - two zinc fingers. Biochem. Biophys. Res. Commun. 273(2000)686-693

Sawada, Y., Miura, Y., Umeki, K., Tamaoki, T., Fujinaga, K., Ohtaki, S. Cloning and characterization of a novel RNA-binding protein SRL300 with RS domains. Biochim. Biophys. Acta 1492(2000)191-195

Sobue, K., Agarwall-Mawal, A., Wei, L., Sun, W., Miura, Y., Paudel, H.K. Interaction of neuronal Cdc2-like protein kinase with microtubule associated protein tau. J. Biol. Chem. 275(2000)16673-16680